Medication-related osteonecrosis of the jaw: Clinical and practical guidelines
نویسندگان
چکیده
منابع مشابه
Medication-Related Osteonecrosis of the Jaw
Osteonecrosis of the jaw (ONJ) is a common side effect of antiresorptive drugs that are administered to cancer patients for bone metastasis, multiple myeloma, and osteoporosis. Since both bisphosphonate (BP) and denosumab show anti-bone resorption effects with ONJ, antiresorptive agent-related ONJ (ARONJ) has been suggested as a comprehensive term encompassing both BP-related osteonecrosis of t...
متن کاملFibrous Dysplasia and Medication-Related Osteonecrosis of the Jaw.
PURPOSE Osteonecrosis of the jaw (ONJ) is an established side effect of intravenous bisphosphonates and other antiresorptive medications. Although bisphosphonates are frequently prescribed for patients with the skeletal disorder fibrous dysplasia (FD), there are no reports of ONJ in this population. This has led some to conclude that patients with FD are at low risk for the development of bisph...
متن کاملBiphosphonates-related osteonecrosis of the jaw: Clinical and physiopathological considerations
Since osteonecrosis of the jaw was related to biphosphonate administration by Marx, studies showing clinical symptoms, drug and surgical therapies overwhelmed the literature. Furthermore, the literature demonstrated the correlation between chronic biphosphonate adsumption and osteonecrosis of the jaw onset. Nitrogen-containing biphosphonates are widely used for the management of metastatic canc...
متن کاملDiabetes Mellitus and Its Association to the Occurrence of Medication-Related Osteonecrosis of the Jaw
To date there is no consensus on the role of diabetes in the development of medication-related osteonecrosis of the jaws (MR-ONJ). Therefore, this study aimed to investigate the prevalence of diabetes and pathological glucose metabolism in patients with MR-ONJ compared to the general population. All maxillofacial surgery inpatients in one year at our department were investigated regarding diagn...
متن کاملBisphosphonate-related osteonecrosis of the jaw
Bisphosphonates (BPs) have been used for the management of bone metabolic diseases. Currently their therapeutic use has increased, as also have their adverse effects, one of the most important being the bisphosphonate-related osteonecrosis of the jaw (BRONJ), a complication of diffi cult treatment and solution. Until now, the physiopathology of BRONJ remains unclear, and its treatment is uncert...
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ژورنال
عنوان ژورنال: Journal of International Society of Preventive and Community Dentistry
سال: 2016
ISSN: 2231-0762
DOI: 10.4103/2231-0762.178742